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BPA Shown to Negatively Impact Brain Development
Posted By admin On March 11, 2013 @ 6:31 am In Sci Tech | Comments Disabled
March 11, 2013
A ubiquitous chemical found in plastics, soup can linings, and receipts, bisphenol-a is just one health-compromising substance that has been under fire for many years. While the scientific community has gathered ample evidence regarding BPAs toxic effects, the chemical is still widely used today. Adding to this evidence, recent research has found that BPA could negatively impact brain development by disrupting a gene responsible for proper nerve cell function.
For the study, which was published in the journal Proceedings of the National Academy of Sciences  and conducted by Duke University researchers , it was discovered that BPA could negative effect central nervous system development by disrupting a gene called Kcc2. With the disruption of this gene, it can no longer properly produce proteins partly responsible for removing chloride from neurons. If chloride can’t be removed, then the functioning of brain cells is hampered.
“Our study found that BPA may impair the development of the central nervous system, and raises the question as to whether exposure could predispose animals and humans to neurodevelopmental disorders,” study researcher Dr. Wolfgang Liedtke, M.D., Ph.D., an associate professor of medicine/neurology and neurobiology at Duke University, said. “Our findings improve our understanding of how environmental exposure to BPA can affect the regulation of the Kcc2 gene. However, we expect future studies to focus on what targets aside from Kcc2 are affected by BPA. This is a chapter in an ongoing story.”
The study abstract concludes with:
“Overall, our results indicate that BPA can disrupt Kcc2 gene expression through epigenetic mechanisms. Beyond increase in basic understanding, our findings have relevance for identifying unique neurodevelopmental toxicity mechanisms of BPA, which could possibly play a role in pathogenesis of human neurodevelopmental disorders.”
Unfortunately, avoiding BPA is quite as easy as it should be. Despite the endocrine-disrupting chemical  being linked to reproductive problems, obesity, diabetes, and now negatively altered brain development, the FDA rejected BPA’s ban  back in March 2012 – so now consumers need to look out for the chemical for years to come.
But there are still many tips for avoiding BPA and even reversing the negative effects sparked by the chemical. Here are a few tips:
PLOS One 
This post originally appeared at Natural Society 
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URLs in this post:
 journal Proceedings of the National Academy of Sciences: http://www.pnas.org/content/early/2013/02/15/1300959110
 by Duke University researchers: http://www.dukehealth.org/health_library/news/bpa-may-affect-the-developing-brain-by-disrupting-gene-regulation
 endocrine-disrupting chemical: http://www.niehs.nih.gov/health/topics/agents/endocrine/index.cfm
 rejected BPA’s ban: http://www.businessweek.com/ap/2012-03/D9TR0GT00.htm
 recycling symbols: http://naturalsociety.com/recycling-symbols-numbers-plastic-bottles-meaning/
 could degrade BPA: http://www.ncbi.nlm.nih.gov/pubmed/17416976
 PLOS One: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0031109
 Natural Society: http://naturalsociety.com/bpa-negatively-impact-brain-development/
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