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Grape Seed Extract Kills Head and Neck Cancer Cells, Leaves Healthy Cells Unharmed

Posted By admin On January 28, 2012 @ 4:57 am In Sci Tech | Comments Disabled

Medical Express [1]
January 28, 2012

Nearly 12,000 people will die of head and neck cancer in the United States this year and worldwide cases will exceed half a million.

A study published this week in the journal Carcinogenesis shows that in both cell lines and mouse models, grape seed extract (GSE) kills head and neck squamous cell carcinoma cells, while leaving healthy cells unharmed.

“It’s a rather dramatic effect,” says Rajesh Agarwal, PhD, investigator at the University of Colorado Cancer Center and professor at the Skaggs School of Pharmaceutical Sciences.

It depends in large part, says Agarwal, on a healthy cell’s ability to wait out damage.

“Cancer cells are fast-growing cells,” Agarwal says. “Not only that, but they are necessarily fast growing. When conditions exist in which they can’t grow, they die.”

Grape seed extract creates these conditions that are unfavorable to growth. Specifically, the paper shows that grape seed extract both damages cancer cells DNA (via increased reactive oxygen species) and stops the pathways that allow repair (as seen by decreased levels of the DNA repair molecules Brca1 and Rad51 and DNA repair foci).

“Yet we saw absolutely no toxicity to the mice, themselves,” Agarwal says.

Again, the grape seed extract killed the cancer cells but not the healthy cells.

Related:

Whole Grape – Seed and Skin – May Be Perfect Colon Cancer Fighting Food [2]

Grape-Seed Extract Kills Laboratory Leukemia Cells [3]


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URLs in this post:

[1] Medical Express: http://medicalxpress.com/news/2012-01-grape-seed-neck-cancer-cells.html

[2] Whole Grape – Seed and Skin – May Be Perfect Colon Cancer Fighting Food: http://medicalxpress.com/news/2011-06-grape-seed-skin-colon.html

[3] Grape-Seed Extract Kills Laboratory Leukemia Cells: http://www.physorg.com/news149924025.html

[4] Non-Disease Virus Kills Breast Cancer Cells In Lab: http://www.prisonplanet.com/non-disease-virus-kills-breast-cancer-cells-in-lab.html

[5] Chemotherapy backfires – causes healthy cells to feed growth of cancer tumors: http://www.prisonplanet.com/chemotherapy-backfires-causes-healthy-cells-to-feed-growth-of-cancer-tumors.html

[6] Breast Milk Found to Protect Against Cancer, Kill Cancer Cells: http://www.prisonplanet.com/breast-milk-found-to-protect-against-cancer-kill-cancer-cells.html

[7] Scientists claim to have identified stem cells that spread cancer: http://www.prisonplanet.com/scientists-claim-to-have-identified-stem-cells-that-spread-cancer.html

[8] Cancer cells slurp up fructose, U.S. study finds: http://www.prisonplanet.com/cancer-cells-slurp-up-fructose-u-s-study-finds.html

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