September 9, 2019
A cocktail of three common drugs appeared to not only slow aging but to reverse it in a small new study published in Nature on Thursday.
Nine people were given a growth hormone and two diabetes drugs for a year as part of the University of California, Los Angeles (UCLA), trial.
By the end of their cycles on the medications, the study participants had, biologically aged 2.5 years – in reverse.
At first blush it looks like a revelation for human health and life expectancy – but the small group of participants were all white men and there was no control group to compare the findings to, drawing some skepticism from experts.
To many, immortality is the holy grail of futurism and medicine.
And even if you don’t idealize the notion of living forever, with aging comes disease and the body’s degradation, so evading the damage that time does to us could mean living a healthier life as well as a longer one.
Much more critical to the length and quality of our lives than our numerical age or the lines on our faces is how our body’s are changing at the cellular and molecular levels.
Scientists gauge biological aging by something called the ‘epigenetic clock.’ One method of doing so was developed by co-author of the new study, UCLA’s Dr Steve Horvath.
This age assessment looks at changes to how DNA is expressed. As we age, chemical tags called methyls start to hang on to molecules of DNA.
Theses pesky changes don’t alter the sequence of the DNA, but they can disrupt the way a section of the genetic code gets turned on and off or issues instructions to biological structures.
This article was posted: Monday, September 9, 2019 at 3:34 am